Zepbound vs Mounjaro vs Tirz: What’s the Difference?
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Tirzepatide is a newer medication that can help with weight loss. It reduces your appetite so you don’t feel as hungry throughout the day. Lots of folks are curious about how much weight they might lose while using this drug.
The initial dose prescribed by your doctor is usually 2.5 mg. This adjusts to your body first and then increases up to 5mg in 4 weeks. So weight loss results depend upon time, does, your lifestyle, and the other modifications you make in your day-to-day life.
Research has shown some promising results. People typically see their weight go down by about 15% to 22% of what they started at. So someone who weighs 200 pounds could expect to lose somewhere between 30 and 44 pounds.
Zepbound vs Mounjaro vs Tirzepatide: What's the Difference?
A lot of confusion is out there about Zepbound vs Mounjaro vs Tirzepatide. Let’s first discuss Tirzepatide and clear the confusion around it.
Tirzepatide
Tirzepatide isn’t a brand name but an ingredient found in both Zepbound and Mounjaro. It’s an advanced ingredient for weight loss that mimics the behavior of the two most common hormones in the body: GLP-1 and GIP.
These hormones help the body produce more insulin, suppress the appetite, and help you lose weight faster. These also help the body use the energy made from food efficiently instead of storing it as fat.
Not only that, but by triggering these hormones, Tirzepatide also helps manage type 2 diabetes. What makes this ingredient stand out is that, unlike other ingredients that only have GLP-1, it has both, which has significantly increased its effects. Both widely known weight loss medicines, Zepbound and Mounjaro, are called Tirzepatide medicines as well because they both contain it.
Zepbound
Zepbound is a weight loss medicine brand created by Eli Lilly. It’s FDA-approved for weight loss and obesity, but not for type 2 diabetes. Its active ingredient is Tirzepatide, which lowers hunger, increases insulin production, and helps the person lose the extra pounds.Though it’s not officially approved for diabetes, its active ingredient may still help manage blood sugar levels. It’s taken as a weekly injection in a prefilled pen or vial.You get to decide what dosage you need based on your doctor’s prescription. The minimum dosages start from 2.5 mg to 15 mg or more if needed.
Mounjaro
It’s another popular FDA-approved medicine for type 2 diabetes created by the Eli Lilly company.This medicine has Tirzepatide, just like Zepbound, and hence it can be great for losing weight. However, it’s created for diabetes but can be used for losing weight as well, along the way to control diabetes.You can take it as a weekly injection, either in its 2.5 mg minimum dosage or the 15 mg. The dosage may vary depending on the requirements of the patient. Your doctor can tell you better what dosage is suitable for you.
Zepbound VS Mounjaro: Main Differences
These are the main differences between Zepbound Vs. Mounjaro:
Point | Zepbound | Mounjaro |
What it is | Tirzepatide for weight loss | Tirzepatide for type 2 diabetes |
Form | Weekly shot, under the skin | Same, weekly injection |
Comes as | Pre-filled pen or single-use vial | Pen or vial too |
Start dose | 2.5 mg weekly, then slowly increased | Same starting plan |
Max dose | Up to 15 mg if needed | Also goes up to 15 mg |
Use length | Long-term, based on goals | Ongoing, depending on diabetes needs |
Age group | Adults 18 and over | Same, 18+ |
Mounjaro Vs Zepbound: FDA-Approved Uses
These are different uses of both of the medicines that the FDA has approved.
Mounjaro
- Lowers blood sugar in type 2 diabetes
- Works with diet and exercise
- Used only for diabetes, not officially for weight loss
Zepbound
- Prescribed for long-term weight control in adults with obesity or excess weight
- Must be combined with lower-calorie meals and more physical activity
- Also approved to aid weight loss in adults with sleep apnea linked to obesity
Are These Medicines Effective?
Yes, both of the medicines are effective and have shown tremendous results when tested in clinical trials. Their effects on weight loss have been incredible.
- Mounjaro users (non-diabetic) lost up to 22.5% weight
- Zepbound led to 15–22.5% weight loss, dose-dependent
- Both worked better than Ozempic and Wegovy for weight loss
Zepbound Vs Mounjaro. Which One Should You Use?
You should use the one that meets your requirements:
- Mounjaro works best for type 2 diabetes and also for weight loss. If you want to lose weight and also manage your diabetes and glucose levels, then you can take this medicine.
- Zepbound is an FDA-approved weight loss medicine. So, if you’re obese and want to shed some pounds, you can use Zepbound.
Potential Side Effects Of Tirepatize Medicines
Before you start taking any of these, make sure you know about the potential disadvantages of Zepbound and Mounjaro.
- An upset stomach is common early on
- Rare risk of pancreatitis
- Avoid if thyroid cancer runs in the family
- Can cause low blood sugar with insulin
Final Words
Tirzepatide is an active ingredient in both Zepbound and the Mounjaro weight loss medicine. It triggers insulin production, lowers hunger, and helps in losing weight.
Zepbound and Mounjaro are the two weight loss medicines that share the same active ingredient, Tirzepatide.
Hence, they’re also called Tirzepatide medicines, owned by only one company, Eli Lilly. Mounjaro works great for people who want to lose weight and also control their diabetes at the same time.
On the other hand, the Zepbound is great for those who’re focused mainly on losing weight, not on managing diabetes. You can choose either, but make sure you consult with your doctor first.
Frequently Asked Question
Is Zepbound the same as Mounjaro?
They share the same ingredient, Tirzepatide, while Zepbound works great for weight loss, and Mounjaro is mainly used for type 2 diabetes.
What is the difference between Mounjaro and Zepbound?
The main difference is the FDA-approved use; Mounjaro treats Type 2 diabetes, while Zepbound targets weight management.
Can you substitute Zepbound for Mounjaro?
Not exactly. Even though they have the same ingredients, they’re approved for different conditions and may not be interchangeable by insurance.
Is tirzepatide the same as Mounjaro and Zepbound?
Yes, Tirzepatide is the active ingredient in both Mounjaro and Zepbound, but they are used for slightly different purposes: Mounjaro is the brand name of tirzepatide approved for type 2 diabetes treatment. Zepbound is the brand name of tirzepatide approved specifically for weight loss (for people who are obese or overweight with at least one weight-related health condition).
Can you substitute Zepbound for Mounjaro?
Yes, but only under doctor supervision. Both contain tirzepatide, but are approved for different uses.
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